Electronic Regulatory Submissions Part 16

The Move to eCTD v4 (Note: This post is part of a multi-part series on the CTD this fall) The eCTD version current at the time of the post is v.3.2.2, with the complete specification contained in this 2008 document. This document has the clearest explanation I’ve...

Electronic Regulatory Submissions Part 15

The Application Lifecycle (Note: This post is part of a multi-part series on the CTD this fall) An NDA or BLA is not a static document; rather, it is a living collection of information that evolves through the lifecycle of the drug. In the earliest lifecycle phases...

Electronic Regulatory Submissions Part 14

Formatting the eCTD (Note: This post is part of a multi-part series on the CTD this fall) It appears to me that the explanations on the eCTD program page are targeted towards those who build XML publishing tools rather than users. That’s one reason why the structure...

Electronic Regulatory Submissions Part 13

How the eCTD Works (Note: This post is part of a multi-part series on the CTD this fall) The eCTD is, at heart, an electronic structure to organize and present submission for ease of review. The specifications for the eCTD are in the FDA’s Technical Conformance...